The patient should consult with the health care practitioner prescribing the Effudex about the use of topical products and before using them, as skin irritation following Effudex treatment is often difficult to resolve, unsightly, and uncomfortable. Cleansing Complex and SHEALD Recovery Balm may be helpful in this situation. Application of SHEALD Recovery Balm may also be alternated with a petrolatum-based product, such as Vaseline or Aquaphor.