There can be tremendous differences between products containing the same ingredients. Although the same ingredient names may appear on packaging of other brands, there is usually a big difference in the quality, purity, and efficacy of those same ingredients. iS Clinical ingredients are the best available globally. Most of the time, these are pharmaceutical grade ingredients that are of the same quality and purity used to make medicines. For example, the pharmaceutical grade Centella asiatica used in iS Clinical products costs 50 or more times as much as the same ingredient used in cosmetic grade products. This cost difference translates into a huge difference in effectiveness (efficacy), tolerability, and benefits to the user.