Although Poly-Vitamin Serum has proven helpful in some conditions involving reddened skin, such as in the iS Cancer Care program. It may be best to first patch test with other skin conditions involving redness or irritation. Poly-Vitamin Serum contains botanical AHAs (Alpha Hydroxy Acids) and is mildly exfoliating. It should not be used in rosacea or on those who are sensitive to Niacin. (see iS Cancer Care training protocols.)