Although iS Clinical products are designed to be extremely safe, use is not recommended for newborns without the specific recommendation from the consulting pediatrician. The pH of newborn skin (approximately 6.6 pH) is slightly more alkaline than adult skin and the immune system of the newborn is not well-developed and undergoes profound changes in a short time. These factors, in addition to other unique medical considerations in the newborn, mandate physician guidance with use of any skin care products.